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Endocrinology

 

  • Bu G, Ying Wang C, Cai G, Leung FC, Xu M, Wang H, Huang G, Li J, Wang Y. Molecular characterization of prolactin receptor (cPRLR) gene in chickens: gene structure, tissue expression, promoter analysis, and its interaction with chicken prolactin (cPRL) and prolactin-like protein (cPRL-L). Mol Cell Endocrinol. 2013 May 6;370(1-2):149-62. doi: 10.1016/j.mce.2013.03.001. Epub 2013 Mar 14. PMID:23499864

  • Kim JE, Leung FC, Jiang J, Kwok AH, Bennett DC, Cheng KM. Expressed sequence tag analysis of the emu (Dromaius novaehollandiae) pituitary by 454 GS Junior pyrosequencing. Poult Sci. 2013 Jan;92(1):90-6. doi: 10.3382/ps.2012-02594. PMID:23243234

  • Li J, Meng F, Song C, Wang Y, Leung FC. Characterization of chicken visfatin gene: cDNA cloning, tissue distribution, and promoter analysis. Poult Sci. 2012 Nov;91(11):2885-94. doi: 10.3382/ps.2012-02315. PMID:23091147

  • Ho JC, Jacobs T, Wang Y, Leung FC. Identification and characterization of the chicken galanin receptor GalR2 and a novel GalR2-like receptor (GalR2-L). Gen Comp Endocrinol. 2012 Nov 1;179(2):305-12. doi: 10.1016/j.ygcen.2012.09.005. Epub 2012 Sep 13. PMID:22982974

  • Kwok AH, Wang Y, Leung FC. Molecular characterization of prostaglandin F receptor (FP) and E receptor subtype 3 (EP3) in chickens. Gen Comp Endocrinol. 2012 Oct 1;179(1):88-98. doi: 10.1016/j.ygcen.2012.07.019. Epub 2012 Aug 4. PMID:22885557

  • Kwok AH, Wang Y, Leung FC. Molecular characterization of prostaglandin F receptor (FP) and E receptor subtype 1 (EP1) in zebrafish. Gen Comp Endocrinol. 2012 Sep 1;178(2):216-26. doi: 10.1016/j.ygcen.2012.05.002. Epub 2012 May 19. PMID:22617193

  • Wang Y, Wang CY, Wu Y, Huang G, Li J, Leung FC. Identification of the receptors for prolactin-releasing peptide (PrRP) and Carassius RFamide peptide (C-RFa) in chickens. Endocrinology. 2012 Apr;153(4):1861-74. doi: 10.1210/en.2011-1719. Epub 2012 Feb 21. PMID:22355069

  • Wang Y, Huang G, Li J, Meng F, He X, Leung FC. Characterization of chicken secretin (SCT) and secretin receptor (SCTR) genes: a novel secretin-like peptide (SCT-LP) and secretin encoded in a single gene. Mol Cell Endocrinol. 2012 Jan 2;348(1):270-80. doi: 10.1016/j.mce.2011.09.012. Epub 2011 Sep 14. PMID:21939730

  • Ho JC, Kwok AH, Zhao D, Wang Y, Leung FC. Characterization of the chicken galanin type I receptor (GalR1) and a novel GalR1-like receptor (GalR1-L). Gen Comp Endocrinol. 2011 Jan 15;170(2):391-400. doi: 10.1016/j.ygcen.2010.10.011. Epub 2010 Oct 25. PMID:20977910

  • Wang Y, Li J, Yan Kwok AH, Ge W, Leung FC. A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: cloning and characterization of its tissue expression. Gen Comp Endocrinol. 2010 Mar 1;166(1):200-10. doi: 10.1016/j.ygcen.2009.10.007. Epub 2009 Oct 23. PMID:19854191

  • Wang Y, Li J, Wang CY, Kwok AY, Zhang X, Leung FC. Characterization of the receptors for chicken GHRH and GHRH-related peptides: identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP). Domest Anim Endocrinol. 2010 Jan;38(1):13-31. doi: 10.1016/j.domaniend.2009.07.008. Epub 2009 Aug 31. PMID:19748756

  • Wang J, Wang Y, Li X, Li J, Leung FC. Cloning, tissue distribution, and functional characterization of chicken glucagon receptor. Poult Sci. 2008 Dec;87(12):2678-88. doi: 10.3382/ps.2008-00260. PMID:19038826

  • Kwok AH, Wang Y, Wang CY, Leung FC. Molecular cloning and characterization of chicken prostaglandin E receptor subtypes 2 and 4 (EP2 and EP4). Gen Comp Endocrinol. 2008 Jun;157(2):99-106. doi: 10.1016/j.ygcen.2008.04.001. Epub 2008 Apr 6. PMID:18486942

  • Wang CY, Wang Y, Kwok AH, Leung FC. Identification of two novel chicken GHRH receptor splice variants: implications for the roles of aspartate 56 in the receptor activation and direct ligand receptor interaction. J Endocrinol. 2007 Dec;195(3):525-36. PMID:18000314

  • Wang Y, Li J, Ying Wang C, Yan Kwok AH, Leung FC. Epidermal growth factor (EGF) receptor ligands in the chicken ovary: I. Evidence for heparin-binding EGF-like growth factor (HB-EGF) as a potential oocyte-derived signal to control granulosa cell proliferation and HB-EGF and kit ligand expression. Endocrinology. 2007 Jul;148(7):3426-40. Epub 2007 Mar 29. PMID:17395697

  • Wang Y, Li J, Wang CY, Kwok AH, Leung FC. Identification of the endogenous ligands for chicken growth hormone-releasing hormone (GHRH) receptor: evidence for a separate gene encoding GHRH in submammalian vertebrates. Endocrinology. 2007 May;148(5):2405-16. Epub 2007 Feb 1. PMID:17272401

  • Kwok AH, Wang Y, Wang CY, Leung FC. Cloning of chicken glucocorticoid receptor (GR) and characterization of its expression in pituitary and extrapituitary tissues. Poult Sci. 2007 Feb;86(2):423-30. PMID:17234861

  • Lau JS, Yip CW, Law KM, Leung FC. Cloning and characterization of chicken growth hormone binding protein (cGHBP). Domest Anim Endocrinol. 2007 Jul;33(1):107-21. Epub 2006 Jun 13. PMID:16814975

  • Wang CY, Wang Y, Li J, Leung FC. Expression profiles of growth hormone-releasing hormone and growth hormone-releasing hormone receptor during chicken embryonic pituitary development. Poult Sci. 2006 Mar;85(3):569-76. PMID:16553291

  • Liang Y, Cui J, Yang G, Leung FC, Zhang X. Polymorphisms of 5' flanking region of chicken prolactin gene. Domest Anim Endocrinol. 2006 Jan;30(1):1-16. Epub 2005 Jun 9. Review. PMID:15970423

  • Ip SC, Lau JS, Au WL, Leung FC. Characterization of the 5'-flanking transcriptional regulatory region of chicken growth hormone gene. Exp Biol Med (Maywood). 2004 Jul;229(7):640-9. PMID:15229358

  • Nie Q, Ip SC, Zhang X, Leung FC, Yang G. New variations in intron 4 of growth hormone gene in Chinese native chickens. J Hered. 2002 Jul-Aug;93(4):277-9. PMID:12407214

  • Au WL, Leung FC. Rapid communication: complete nucleotide sequence of the chicken prolactin gene. J Anim Sci. 2002 May;80(5):1381. No abstract available. PMID:12019630

  • Ip SC, Zhang X, Leung FC. Genomic growth hormone gene polymorphisms in native Chinese chickens. Exp Biol Med (Maywood). 2001 May;226(5):458-62. PMID:11393175

  • Leung FC. Circadian rhythms of melatonin release from chicken pineal in vitro: modified melatonin radioimmunoassay. Proc Soc Exp Biol Med. 1991 Dec;198(3):826-32. PMID:1946475

  • Leung FC, Bohn LR, Dagle GE. Elevated epidermal growth factor receptor binding in plutonium-induced lung tumors from dogs. Proc Soc Exp Biol Med. 1991 Apr;196(4):385-9. PMID:2008439

  • Leung FC. Growth factor and growth factor receptor in radiation carcinogenesis. Radiat Environ Biophys. 1991;30(3):191-4. Review. No abstract available. PMID:1924704

  • Leung FC, Bowen DL, Chandler DP. Construction of a biologically active recombinant DNA plasmid containing a mouse metallothionein promoter and genomic bovine growth hormone gene. Nucleic Acids Res. 1990 Aug 25;18(16):4942. No abstract available. PMID:2395666

  • Martin-Gallardo A, Montoya-Zavala M, Kelder B, Taylor J, Chen H, Leung FC, Kopchick JJ. A comparison of bovine growth-hormone gene expression in mouse L cells directed by the Moloney murine-leukemia virus long terminal repeat, simian virus-40 early promoter or cytomegalovirus immediate-early promoter. Gene. 1988 Oct 15;70(1):51-6. PMID:2853691

  • Thommes RC, Umporowicz DM, Leung FC, Woods JE. Ontogenesis of immunocytochemically demonstrable somatotrophs in the adenohypophyseal pars distalis of the developing chick embryo. Gen Comp Endocrinol. 1987 Sep;67(3):390-8. PMID:3666413

  • Leung FC, Styles WJ, Rosenblum CI, Lilburn MS, Marsh JA. Diminished hepatic growth hormone receptor binding in sex-linked dwarf broiler and leghorn chickens. Proc Soc Exp Biol Med. 1987 Feb;184(2):234-8. PMID:3809176

  • Taylor JE, Ball CA, Leung FC. Interaction of human pancreatic growth hormone-releasing factor, thyrotropin-releasing hormone, and somatostatin on growth hormone release in chickens. Proc Soc Exp Biol Med. 1986 Dec;183(3):363-7. PMID:2879290

  • Leung FC, Jones B, Steelman SL, Rosenblum CI, Kopchick JJ. Purification and physiochemical properties of a recombinant bovine growth hormone produced by cultured murine fibroblasts. Endocrinology. 1986 Oct;119(4):1489-96. PMID:3757900

  • Lilburn MS, Leung FC, Ngiam-Rilling K, Smith JH. The relationship between age and genotype and circulating concentrations of triiodothyronine (T3), thyroxine (T4), and growth hormone in commercial meat strain chickens. Proc Soc Exp Biol Med. 1986 Jul;182(3):336-43. PMID:3714715

  • Lilburn MS, Ngiam-Rilling K, Leung FC, Smith JH. The relationship between age and genotype and the growth of commercial meat strain chickens. Proc Soc Exp Biol Med. 1986 Jul;182(3):328-35. PMID:3714715

  • Leung FC, Taylor JE, Wien S, Van Iderstine A. Purified chicken growth hormone (GH) and a human pancreatic GH-releasing hormone increase body weight gain in chickens. Endocrinology. 1986 May;118(5):1961-5. PMID:3084211

  • Leung FC. Avian hormones. Basic Life Sci. 1986;37:113-25. No abstract available. 

  • Kopchick JJ, Pasleau F, Leung FC. Expression of the bovine growth hormone gene in cultured rodent cells. Basic Life Sci. 1986;37:19-37. No abstract available. PMID:3010933

  • Leung FC, Taylor JE, Van Iderstine A. Effects of dietary thyroid hormones on growth, plasma T3 and T4, and growth hormone in normal and hypothyroid chickens. Gen Comp Endocrinol. 1985 Jul;59(1):91-9. PMID:4018556

  • Burch WM, Corda G, Kopchick JJ, Leung FC. Homologous and heterologous growth hormones fail to stimulate avian cartilage growth in vitro. J Clin Endocrinol Metab. 1985 Apr;60(4):747-50. PMID:4038715

  • Kopchick JJ, Malavarca RH, Livelli TJ, Leung FC. Use of avian retroviral-bovine growth hormone DNA recombinants to direct expression of biologically active growth hormone by cultured fibroblasts. DNA. 1985 Feb;4(1):23-31. PMID:2982557

  • Leung FC, Taylor JE, Steelman SL, Bennett CD, Rodkey JA, Long RA, Serio R, Weppelman RM, Olson G. Purification and properties of chicken growth hormone and the development of a homologous radioimmunoassay. Gen Comp Endocrinol. 1984 Dec;56(3):389-400.

  • Leung FC, Taylor JE, Van Iderstine A. Effects of dietary thyroid hormones on growth and serum T3, T4, and growth hormone in sex-linked dwarf chickens. Proc Soc Exp Biol Med. 1984 Oct;177(1):77-81. PMID:6096203

  • Leung FC, Taylor JE, van Iderstine A. Thyrotropin-releasing hormone stimulates body weight gain and increases thyroid hormones and growth hormone in plasma of cockerels. Endocrinology. 1984 Aug;115(2):736-40. PMID:6430679

  • Leung FC, Taylor JE. In vivo and in vitro stimulation of growth hormone release in chickens by synthetic human pancreatic growth hormone releasing factor (hpGRFs). Endocrinology. 1983 Nov;113(5):1913-5. PMID:6138249

  • Leung FC, Alysworth CF, Meites J. Counteraction of underfeeding-induced inhibition of mammary tumor growth in rats by prolactin and estrogen administration. Proc Soc Exp Biol Med. 1983 May;173(1):159-63. PMID:6856617

  • Van Vugt DA, Aylsworth CF, Sylvester PW, Leung FC, Meites J. Evidence for hypothalamic noradrenergic involvement in naloxone-induced stimulation of luteinizing hormone release. Neuroendocrinology. 1981 Nov;33(5):261-4. PMID:7301047

  • Leung FC, Chen HT, Verkaik SJ, Steger RW, Peluso JJ, Campbell GA, Meites J. Mechanism(s) by which adrenalectomy and corticosterone influence prolactin release in the rat. J Endocrinol. 1980 Oct;87(1):131-40. No abstract available. PMID:7430912

  • Steger RW, Peluso JJ, Huang HH, Hodson CA, Leung FC, Meites J, Sacher G. Effects of advancing age on the hypothalamic-pituitary-ovarian axis of the female white-footed mouse (Peromyscus leucopus). Exp Aging Res. 1980 Aug;6(4):329-39. PMID:7000517

  • Aylsworth CF, Sylvester PW, Leung FC, Meites J. Inhibition of mammary tumor growth by dexamethasone in rats in the presence of high serum prolactin levels. Cancer Res. 1980 Jun;40(6):1863-6. PMID:7371016

  • Steger RW, Huang HH, Hodson CA, Leung FC, Meites J, Sacher GA. Effects of advancing age on hypothalamic-hypophysial-testicular functions in the male white-footed mouse (Peromyscus leucopus). Biol Reprod. 1980 May;22(4):805-9. No abstract available. PMID:6994828

  • Leung FC. Relationship between radioreceptor assay and radioimmunoassay estimates of prolactin in rat pituitary tissue, incubation medium, and serum: effects of dialysis on measurements of the hormone. Endocrinology. 1980 Jan;106(1):61-7. No abstract available. PMID:7349973

  • Leung FC, Russell SM, Nicoll CS. Relationship between bioassay and radioimmunoassay estimates of prolactin in rat serum. Endocrinology. 1978 Nov;103(5):1619-28. PMID:570911

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